Probiotics as immunomodulators: substances, mechanisms and therapeutic benefits
نویسندگان
چکیده
The human gut symbionts in whole and probiotics in particular promote intestinal function and health, partially via modulation of gut associated lymphoid tissue. Molecular basis of microbiota-host interaction is pattern recognition receptors (PRRs) and their ligands, viz., microbe-associated molecular patterns (MAMP). Immunomodulatory effects of probiotics are strain-specific, which is important to select specific strains suitable for treatment/prevention of infectious diseases, food allergy and non-infectious inflammatory diseases including autoimmune disorders.
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